Publicaciones sobre arsénico y estrés oxidativo

21.-  Mourenza Á, Gil JA, Mateos LM, Letek M. Oxidative Stress-Generating Antimicrobials, a Novel Strategy to Overcome Antibacterial Resistance. Antioxidants (Basel). 2020 Apr 26;9(5):E361. Pubmed.

20.- Mourenza Á, Collado C, Bravo-Santano N, Gil JA, Mateos LM, Letek M. The extracellular thioredoxin Etrx3 is required for macrophage infection in Rhodococcus equi. Vet Res. 2020 Mar 10;51(1):38. Pubmed.

19.- Mourenza Á, Gil JA, Mateos LM, Letek M. A Novel Screening Strategy Reveals ROS-Generating Antimicrobials That Act Synergistically against the Intracellular Veterinary Pathogen Rhodococcus equi. Antioxidants (Basel). 2020 Jan 28;9(2):114. Pubmed.

18.- Tossounian MA, Khanh Truong AC, Buts L, Wahni K, Mourenza Á, Leermakers M, Vertommen D, Mateos LM, Volkov AN, Messens J. Methionine sulfoxide reductase B from Corynebacterium diphtheriae catalyzes sulfoxide reduction via an intramolecular disulfide cascade.
J Biol Chem. 2020 Mar 13;295(11):3664-3677. Pubmed

17.- Mourenza Á, Bravo-Santano N, Pradal I, Gil JA, Mateos LM, Letek M.  Mycoredoxins Are Required for Redox Homeostasis and Intracellular Survival in the Actinobacterial Pathogen Rhodococcus equi.
Antioxidants (Basel). 2019 Nov 15;8(11):558. Pubmed

16.- Pedre B, Young D, Charlier D, Mourenza Á, Rosado LA, Marcos-Pascual L, Wahni K, Martens E, G de la Rubia A, Belousov VV, Mateos LM, Messens J. Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2 sensing. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11623-E11632. Pubmed. 

15.-  Rosado LA, Wahni K, Degiacomi G, Pedre B, Young D, de la Rubia AG, Boldrin F, Martens E, Marcos-Pascual L, Sancho-Vaello E, Albesa-Jové D, Provvedi R, Martin C, Makarov V, Versées W, Verniest G, Guerin ME, Mateos LM, Manganelli R, Messens J. The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis. J Biol Chem. 2017 Aug 11;292(32):13097-13110. Pubmed.

14.- Mateos LM, Villadangos AF, de la Rubia AG, Mourenza A, Marcos-Pascual L, Letek M, Pedre B, Messens J, Gil JA. The Arsenic Detoxification System in Corynebacteria: Basis and Application for Bioremediation and Redox Control. Adv Appl Microbiol. 2017;99:103-137. Pubmed. 

13.- Pedre B, Van Molle I, Villadangos AF, Wahni K, Vertommen D, Turell L, Erdogan H, Mateos LM, Messens.   The Corynebacterium glutamicum mycothiol peroxidase is a reactive oxygen species-scavenging enzyme that shows promiscuity in thiol redox control. J.Mol Microbiol. 2015 Jun;96(6):1176-1191. Pubmed

12.- Van Laer K, Dziewulska AM, Fislage M, Wahni K, Hbeddou A, Collet JF, Versées W, Mateos LM, Tamu-Dufe V Messens J. Mycobacterium tuberculosis and Corynebacterium glutamicum NrdH-redoxins form dimers at high protein concentration and exclusively receive electrons from thioredoxin reductase. J Biol Chem (2013) 288: 7942-7955. PubMed.

11.- Van Laer K, Buts L, Foloppe N, Vertommen D, Van Belle K, Wahni K, Roos G, Nilsson L, Mateos LM, Rawat M, Van Nuland NAJ and Messens J. Mycoredoxin-1 is one of the missing links in the oxidative stress defense mechanism of Mycobacterium tuberculosis. Mol Microbiol (2012) 86: 787-804. PubMed.

10.- Efren Ordoñez, Almudena F. Villadangos, María Fiuza, Fernando J. Pereira, José A. Gil, Luis M. Mateos and A. Javier Aller.. Modelling of arsenate retention from aqueous solutions by living coryneform double-mutant bacteria.  Environ Chem (2012) 9: 121-129. Acceder.

9.- Almudena F. Villadangos, Hsueh-Liang Fu, Jose A Gil, Joris Messens, Barry P Rosen, Luis M Mateos. The efflux permease CgAcr3-1 of Corynebacterium glutamicum is an arsenite-specific antiporter. J Biol Chem (2012) 287: 723-725. PubMed.

8.- Almudena F. Villadangos, Karolien Van Belle, Khadija Wahni, Veronica Tamu Dufe, Sofia Freitas, Haneen Nur, Sandra De Galan, José A Gil, Jean-Francois Collet, Luis M Mateos, Joris Messens. Corynebacterium glutamicum survives arsenic stress with arsenate reductases coupled to two distinct redox mechanisms. Mol Microbiol (2011) 82: 998-1014. PubMed.

7.- A.F. Villadangos, E. Ordóñez, M.I. Muñoz, I.M. Pastrana, M. Fiuza, J.A. Gil, L.M. Mateos, A.J. Aller. Retention of arsenate using genetically modified coryneform bacteria and determination of arsenic in solid samples by ICP-MS. Talanta 80 (2010): 1421-1427. PubMed.

6.- Hseuh-Liang Fu, Yuling Meng, Efrén Ordóňez, Almudena F. Villadangos, Hiranmoy Bhattacharjee, José A. Gil, Luís M. Mateos and Barry P. Rosen. Properties of Acr3 arsenite efflux permeases from Alkaliphilus metalliredigens and Corynebacterium glutamicum. J Biol Chem 284 (2009):19887-19895. PubMed.

5.- Efrén Ordóñez, Karolien Van Belle, Goedele Roos, Sandra De Galan, Michal Letek, Jose A. Gil, Lode Wyns, Luis M. Mateos, and Joris Messens. Arsenate reductase, mycothiol and mycoredoxin concert thiol/disulfide exchange. J. Biol. Chem. 284 (2009): 15107-15116. PubMed.

4.- Efrén Ordóñez, Saravanamuthu Thiyagarajan, Jeremy D. Cook, Timothy L. Stemmler, José A. Gil, Luís M. Mateos and Barry P. Rosen. Evolution of metal(loid) binding sites in transcriptional regulators. J. Biol. Chem., 283 (2008): 25706-25714. PubMed.

3.- J.C. Feo, E. Ordoñez, M. Letek, M.A. Castro, M.I. Muñoz, J.A. Gil, L.M. Mateos and A.J. Aller. Retention of inorganic arsenic by coryneform mutant strains. Water Res. 41 (2007) 531 – 542. PubMed.

2.- Luís M. Mateos, Efrén Ordóñez, Michal Letek, and José A. Gil. Corynebacterium glutamicum as a model bacterium for the bioremediation of arsenic. Int. Microbiol 9 (2006): 207-215. PubMed.

1.- Efrén Ordóñez, Michal Letek, Noelia Valbuena, José A. Gil and Luis M. Mateos. Analysis of genes involved in arsenic resistance in Corynebacterium glutamicum ATCC13032. Appl. Environ. Microbiol. 71 (2005) 6206-6215. PubMed.